To create a personalized plan, we assess your medical history, symptoms, and treatment goals.
Esketamine Spravato Therapy
Esketamine is a drug derived from ketamine that can be used in the treatment of depression. Esketamine can be administered as a nasal spray, which is referred to as Spravato under its brand name. Spravato is self-administered under supervision by a medical professional to ensure safe and appropriate use of the medication.
Most major insurance companies cover Spravato including Medicare
FDA approved for treating adults with treatment-resistant depression
Patients may notice a difference within a matter of hours
Book Your Consultation Now
Not sure which treatment is right for you? Take the quiz →
Contact Us
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We will get back to you as soon as possible.
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Esketamine Spravato Therapy
Esketamine is a drug derived from ketamine that can be used in the treatment of depression. Esketamine can be administered as a nasal spray, which is referred to as Spravato under its brand name. Spravato is self-administered under supervision by a medical professional to ensure safe and appropriate use of the medication.
Most major insurance companies cover Spravato including Medicare
FDA approved for treating adults with treatment-resistant depression
Patients may notice a difference within a matter of hours
Book Your Consultation Now
Not sure which treatment is right? Take the quiz →
Contact Us
Thank you for contacting us.
We will get back to you as soon as possible.
We will get back to you as soon as possible.
Oops, there was an error sending your message.
Please try again later.
Please try again later.
Esketamine Spravato Therapy
Esketamine is a drug derived from ketamine that can be used in the treatment of depression. Esketamine can be administered as a nasal spray, which is referred to as Spravato under its brand name. Spravato is self-administered under supervision by a medical professional to ensure safe and appropriate use of the medication.
Want to talk? Give us a call at
Most major insurance companies cover Spravato including Medicare
FDA approved for treating adults with treatment-resistant depression
Patients may notice a difference within a matter of hours
Book Your Consultation Now
Not sure which treatment is right? Take the quiz →
Contact Us
Thank you for contacting us.
We will get back to you as soon as possible.
We will get back to you as soon as possible.
Oops, there was an error sending your message.
Please try again later.
Please try again later.
I did not have any expectations about visiting Dr Knightly as I have seen other professionals in the past and some were not very good; and others were mediocre. Very few were excellent. But he takes Medicare which is a huge benefit. Most do not. And I found him to be very professional; warm and engaging. Whether I will really feel differently or not remains to be seen. But the experience was overall a very good one and I would recommend him to anyone.
Lisa Foley
Jun 5, 2023
I did not have any expectations about visiting Dr Knightly as I have seen other professionals in the past and some were not very good; and others were mediocre. Very few were excellent. But he takes Medicare which is a huge benefit. Most do not. And I found him to be very professional; warm and engaging. Whether I will really feel differently or not remains to be seen. But the experience was overall a very good one and I would recommend him to anyone.
Lisa Foley
Jun 5, 2023
What Is Esketamine (Spravato)?
Leading Esketamine Therapy For Depression in Connecticut
Esketamine’s primary mechanism of action is via the glutamatergic system. It increases the levels of available glutamate, which is a neurotransmitter that plays a crucial role in mood regulation and synaptic plasticity. It is believed that esketamine can lead to the generation of new neural pathways leading to its rapid antidepressant effects.
Who is Spravato For?
Spravato has been approved by the FDA for treating adults with
treatment-resistant depression, who have tried at least two other forms of oral antidepressants.
Although ketamine has been researched as a treatment for anxiety, esketamine has not yet been examined for this purpose.
The Benefits of Spravato Therapy
The low dosage requirement of Spravato means that side effects are generally less common and more mild. Furthermore, unlike regular antidepressants, esketamine takes immediate effect - patients may notice a difference within a matter of hours, even regarding suicidal ideation.
At Evolve, we understand how difficult it can be trialing standard antidepressants, with possible complications when adjusting to prescribed medication and navigating side effects, all while waiting for the
medication to take effect. As such, we highly recommend Spravato for those who seek rapid relief.
Is Esketamine Different From Ketamine?
Esketamine is a molecule derived from ketamine, though it has different medical purposes. Ketamine’s primary medical function is as an anesthetic and for short-term sedation. Although Ketamine has been researched as a medication for treatment-resistant depression, it has not been FDA-approved, unlike esketamine.
Esketamine, which has received FDA approval, has been thoroughly researched in individuals experiencing suicidality and treatment-resistant depression. Unique to esketamine, the esketamine molecule can be absorbed through the nasal mucosa, making delivery of the drug less invasive in comparison to intravenous ketamine.¹
What Does Spravato Feel Like?
We appreciate that you will want to familiarize yourself with how Spravato is administered and feels.
Many patients report mild feelings of dissociation and disconnection from their bodies after receiving Spravato. This is a result of the anesthetic effect of ketamine. Though it may feel confusing or disorienting, it is not a painful experience. In addition to this, the sedative effect may lead to drowsiness, lasting up to a few hours after administration.
These side effects may be considered somewhat unique in comparison to other common medications. It is our priority to ensure your safety and comfort through professional supervision when Spravato is administered.
Will My Insurance Cover Spravato?
Most major insurance companies cover Spravato treatment, including commercial plans as well as Medicare.
Esketamine (Spravato) at Evolve Brain Health
Thank you for considering us at Evolve Brain Health in making plans to combat your difficulties with depression. If your previous attempts at managing your depressive symptoms have led to minor progress, we can offer a novel and promising solution with Spravato. Led by Dr. Thomas Knightly, a clinical associate professor at the world-renowned Brain Stimulation Lab at Stanford University, we will ensure that your entire treatment is comfortable and completed to the highest standard.
References
1 Quintana, D. S., Steen, N. E., & Andreassen, O. A. (2018). The promise of intranasal esketamine as a novel and effective antidepressant. JAMA psychiatry, 75(2), 123-124.
Related Services
Book Consultation →
What Happens In My Consultation?
You'll have an open conversation with your psychiatrist to discuss options and next steps.
A tailored approach is developed based on your unique needs, ensuring the best outcomes for you.
What Is Esketamine (Spravato)?
Leading Esketamine Therapy For Depression in Connecticut
Esketamine’s primary mechanism of action is via the glutamatergic system. It increases the levels of available glutamate, which is a neurotransmitter that plays a crucial role in mood regulation and synaptic plasticity. It is believed that esketamine can lead to the generation of new neural pathways leading to its rapid antidepressant effects.
Who is Spravato For?
Spravato has been approved by the FDA for treating adults with
treatment-resistant depression, who have tried at least two other forms of oral antidepressants.
Although ketamine has been researched as a treatment for anxiety, esketamine has not yet been examined for this purpose.
The Benefits of Spravato Therapy
The low dosage requirement of Spravato means that side effects are generally less common and more mild. Furthermore, unlike regular antidepressants, esketamine takes immediate effect - patients may notice a difference within a matter of hours, even regarding suicidal ideation.
At Evolve, we understand how difficult it can be trialing standard antidepressants, with possible complications when adjusting to prescribed medication and navigating side effects, all while waiting for the
medication to take effect. As such, we highly recommend Spravato for those who seek rapid relief.
Is Esketamine Different From Ketamine?
Esketamine is a molecule derived from ketamine, though it has different medical purposes. Ketamine’s primary medical function is as an anesthetic and for short-term sedation. Although Ketamine has been researched as a medication for treatment-resistant depression, it has not been FDA-approved, unlike esketamine.
Esketamine, which has received FDA approval, has been thoroughly researched in individuals experiencing suicidality and treatment-resistant depression. Unique to esketamine, the esketamine molecule can be absorbed through the nasal mucosa, making delivery of the drug less invasive in comparison to intravenous ketamine.¹
What Does Spravato Feel Like?
We appreciate that you will want to familiarize yourself with how Spravato is administered and feels.
Many patients report mild feelings of dissociation and disconnection from their bodies after receiving Spravato. This is a result of the anesthetic effect of ketamine. Though it may feel confusing or disorienting, it is not a painful experience. In addition to this, the sedative effect may lead to drowsiness, lasting up to a few hours after administration.
These side effects may be considered somewhat unique in comparison to other common medications. It is our priority to ensure your safety and comfort through professional supervision when Spravato is administered.
Will My Insurance Cover Spravato?
Most major insurance companies cover Spravato treatment, including commercial plans as well as Medicare.
Esketamine (Spravato) at Evolve Brain Health
Thank you for considering us at Evolve Brain Health in making plans to combat your difficulties with depression. If your previous attempts at managing your depressive symptoms have led to minor progress, we can offer a novel and promising solution with Spravato. Led by Dr. Thomas Knightly, a clinical associate professor at the world-renowned Brain Stimulation Lab at Stanford University, we will ensure that your entire treatment is comfortable and completed to the highest standard.
References
1 Quintana, D. S., Steen, N. E., & Andreassen, O. A. (2018). The promise of intranasal esketamine as a novel and effective antidepressant. JAMA psychiatry, 75(2), 123-124.
Related Services
Book Consultation →
What Happens In My Consultation?
To create a personalized plan, we assess your medical history, symptoms, and treatment goals.
You'll have an open conversation with your psychiatrist to discuss options and next steps.
A tailored approach is developed based on your unique needs, ensuring the best outcomes for you.
What Is Esketamine (Spravato)?
Leading Esketamine Therapy For Depression in Connecticut
Esketamine’s primary mechanism of action is via the glutamatergic system. It increases the levels of available glutamate, which is a neurotransmitter that plays a crucial role in mood regulation and synaptic plasticity. It is believed that esketamine can lead to the generation of new neural pathways leading to its rapid antidepressant effects.
Who is Spravato For?
Spravato has been approved by the FDA for treating adults with
treatment-resistant depression, who have tried at least two other forms of oral antidepressants.
Although ketamine has been researched as a treatment for anxiety, esketamine has not yet been examined for this purpose.
The Benefits of Spravato Therapy
The low dosage requirement of Spravato means that side effects are generally less common and more mild. Furthermore, unlike regular antidepressants, esketamine takes immediate effect - patients may notice a difference within a matter of hours, even regarding suicidal ideation.
At Evolve, we understand how difficult it can be trialing standard antidepressants, with possible complications when adjusting to prescribed medication and navigating side effects, all while waiting for the
medication to take effect. As such, we highly recommend Spravato for those who seek rapid relief.
Is Esketamine Different From Ketamine?
Esketamine is a molecule derived from ketamine, though it has different medical purposes. Ketamine’s primary medical function is as an anesthetic and for short-term sedation. Although Ketamine has been researched as a medication for treatment-resistant depression, it has not been FDA-approved, unlike esketamine.
Esketamine, which has received FDA approval, has been thoroughly researched in individuals experiencing suicidality and treatment-resistant depression. Unique to esketamine, the esketamine molecule can be absorbed through the nasal mucosa, making delivery of the drug less invasive in comparison to intravenous ketamine.¹
What Does Spravato Feel Like?
We appreciate that you will want to familiarize yourself with how Spravato is administered and feels.
Many patients report mild feelings of dissociation and disconnection from their bodies after receiving Spravato. This is a result of the anesthetic effect of ketamine. Though it may feel confusing or disorienting, it is not a painful experience. In addition to this, the sedative effect may lead to drowsiness, lasting up to a few hours after administration.
These side effects may be considered somewhat unique in comparison to other common medications. It is our priority to ensure your safety and comfort through professional supervision when Spravato is administered.
Will My Insurance Cover Spravato?
Most major insurance companies cover Spravato treatment, including commercial plans as well as Medicare.
Esketamine (Spravato) at Evolve Brain Health
Thank you for considering us at Evolve Brain Health in making plans to combat your difficulties with depression. If your previous attempts at managing your depressive symptoms have led to minor progress, we can offer a novel and promising solution with Spravato. Led by Dr. Thomas Knightly, a clinical associate professor at the world-renowned Brain Stimulation Lab at Stanford University, we will ensure that your entire treatment is comfortable and completed to the highest standard.
References
1 Quintana, D. S., Steen, N. E., & Andreassen, O. A. (2018). The promise of intranasal esketamine as a novel and effective antidepressant. JAMA psychiatry, 75(2), 123-124.
Related Services
Book Consultation →
What Happens In My Consultation?
To create a personalized plan, we assess your medical history, symptoms, and treatment goals.
You'll have an open conversation with your psychiatrist to discuss options and next steps.
A tailored approach is developed based on your unique needs, ensuring the best outcomes for you.
Start Treatment
Start your journey to better mental health and well-being today. Take our online quiz to find the best treatment option for you, or give us a call to book your free consultation.
Not Sure Which Treatment Is Right?
Take our quick quiz to get personalized recommendations based on your needs.
Not Sure Which Treatment Is Right?
Take our quick quiz to get personalized recommendations based on your needs.
Not Sure Which Treatment Is Right?
Take our quick quiz to get personalized recommendations based on your needs.
Why Choose Us?
We are committed to providing evidence-based treatments that offer real, lasting results.
Expert Care
Board-certified psychiatrist with extensive experience in mental health therapies.
Insurance Accepted
We accept all major insurance providers, including Medicare.
Accelerated Recovery
Our 5-day accelerated TMS program helps you get better, faster.
Individualized
Tailored treatment plans designed just for you.
Holistic Approach
We offer TMS and Esketamine to enhance the effectiveness of psychotherapy.
FDA-Approved
Our treatments meet the highest safety and efficacy standards.
Read Our Patient Reviews
"I highly recommend Evolve Brain Health if you are considering TMS. My experience was extremely positive. Dr. Knightly is very bright, compassionate and patient. He took time to answer all of my questions without ever making me feel rushed. It’s very easy to schedule appointments and always runs right on time. The treatment is very easy-in and out in less than 15 minutes with no side effects!"
Gerrianne D.
"Dr. Knightly was without a doubt, one of the most professional, knowledgeable and experienced Psychiatrists I have ever seen. Honestly, it was an appointment I would look forward to, rather than just any generic Doctor visit, which we all definitely know is not where we want to be. His follow up and true commitment to his patients is hard to find these days. 5 Stars is not enough. He is better than any rating scale and I know will humbly continue to help as many people as he can."
Michael.
"Dr Knightly is empathetic, professional & informative. He’s walked me through the process & has answered all my questions without hesitation, even the questions I’ve repeatedly asked. During my first session I was overwhelmed with emotion (I’ve tried many things to try to treat my depression) & he validated my experience & made me feel comfortable. I recommend anyone who is interested in TMS to visit his office, you‘re in good hands."
Jade C.
Why Choose Us?
We are committed to providing evidence-based treatments that offer real, lasting results.
Expert Care
Board-certified psychiatrist with extensive experience in mental health therapies.
Insurance Accepted
We accept all major insurance providers, including Medicare.
Accelerated Recovery
Our 5-day accelerated TMS program helps you get better, faster.
Individualized
Tailored treatment plans designed just for you.
Holistic Approach
We offer TMS and Esketamine to enhance the effectiveness of psychotherapy.
FDA-Approved
Our treatments meet the highest safety and efficacy standards.
Read Our Patient Reviews
"I highly recommend Evolve Brain Health if you are considering TMS. My experience was extremely positive. Dr. Knightly is very bright, compassionate and patient. He took time to answer all of my questions without ever making me feel rushed. It’s very easy to schedule appointments and always runs right on time. The treatment is very easy-in and out in less than 15 minutes with no side effects!"
Gerrianne D.
"Dr. Knightly was without a doubt, one of the most professional, knowledgeable and experienced Psychiatrists I have ever seen. Honestly, it was an appointment I would look forward to, rather than just any generic Doctor visit, which we all definitely know is not where we want to be. His follow up and true commitment to his patients is hard to find these days. 5 Stars is not enough. He is better than any rating scale and I know will humbly continue to help as many people as he can."
Michael.
"Dr Knightly is empathetic, professional & informative. He’s walked me through the process & has answered all my questions without hesitation, even the questions I’ve repeatedly asked. During my first session I was overwhelmed with emotion (I’ve tried many things to try to treat my depression) & he validated my experience & made me feel comfortable. I recommend anyone who is interested in TMS to visit his office, you‘re in good hands."
Jade C.
Will My Insurance Cover TMS Therapy?
We can help verify your benefits and provide transparent pricing options so you can plan your treatment confidently.
Featured Resources
Interested in learning about various mental health treatments? Visit our Learning Center for clear, easy-to-understand explanations of procedures, protocols, comparisons, and the conditions they address.
What to Expect In Each Treatment
Beginning therapy can be a daunting experience. By informing you what one might expect from each treatment, we aim to ease this process and minimize the stress around seeking support for your mental health.
Is TMS Therapy Right For Me?
As TMS is a novel approach to mental health treatment, you may not have heard about it. This quiz can help you learn whether you are interested in TMS based on your symptoms, but it is not a comprehensive decision tool.
Our Guide to Help You Choose Your Treatment
Beginning therapy can be difficult enough without being overwhelmed by the variety of treatment options. In this article, we cover the differences between our services to help you decide which treatment you may want to pursue with us.
What to Expect In Each Treatment
Beginning therapy can be a daunting experience. By informing you what one might expect from each treatment, we aim to ease this process and minimize the stress around seeking support for your mental health.
Is TMS Therapy Right For Me?
As TMS is a novel approach to mental health treatment, you may not have heard about it. This quiz can help you learn whether you are interested in TMS based on your symptoms, but it is not a comprehensive decision tool.
Our Guide to Help You Choose Your Treatment
Beginning therapy can be difficult enough without being overwhelmed by the variety of treatment options. In this article, we cover the differences between our services to help you decide which treatment you may want to pursue with us.
Book Your Consultation
Take the first step towards better mental health and well-being. Call us at
(203) 504-9758
or complete the form below.
Contact Us
Thank you for contacting us.
We will get back to you as soon as possible.
We will get back to you as soon as possible.
Oops, there was an error sending your message.
Please try again later.
Please try again later.
What Happens In My Consultation?
To create a personalized plan, we assess your medical history, symptoms, and treatment goals.
You'll have an open conversation with your psychiatrist to discuss options and next steps.
A tailored approach is developed based on your unique needs, ensuring the best outcomes for you.
(203) 504-9758
Will My Insurance Cover TMS Therapy?
We can help verify your benefits and provide transparent pricing options so you can plan your treatment confidently.
Featured Resources
Interested in learning about various mental health treatments? Visit our Learning Center for clear, easy-to-understand explanations of procedures, protocols, comparisons, and the conditions they address.
What to Expect In Each Treatment
Beginning therapy can be a daunting experience. By informing you what one might expect from each treatment, we aim to ease this process and minimize the stress around seeking support for your mental health.
Is TMS Therapy Right For Me?
As TMS is a novel approach to mental health treatment, you may not have heard about it. This quiz can help you learn whether you are interested in TMS based on your symptoms, but it is not a comprehensive decision tool.
Our Guide to Help You Choose Your Treatment
Beginning therapy can be difficult enough without being overwhelmed by the variety of treatment options. In this article, we cover the differences between our services to help you decide which treatment you may want to pursue with us.
Book Your Consultation
Take the first step towards better mental health and well-being. Call us at
(203) 504-9758
or complete the form below.
Contact Us
Thank you for contacting us.
We will get back to you as soon as possible.
We will get back to you as soon as possible.
Oops, there was an error sending your message.
Please try again later.
Please try again later.
What Happens In My Consultation?
To create a personalized plan, we assess your medical history, symptoms, and treatment goals.
You'll have an open conversation with your psychiatrist to discuss options and next steps.
A tailored approach is developed based on your unique needs, ensuring the best outcomes for you.
(203) 504-9758
Why Choose Us?
We are committed to providing evidence-based treatments that offer real, lasting results.
Expert Care
Board-certified psychiatrist with extensive experience in mental health therapies.
Insurance Accepted
We accept all major insurance providers, including Medicare.
Accelerated Recovery
Our 5-day accelerated TMS program helps you get better, faster.
Individualized
Tailored treatment plans designed just for you.
Holistic Approach
We offer TMS and Esketamine to enhance the effectiveness of psychotherapy.
FDA-Approved
Our treatments meet the highest safety and efficacy standards.
Read Our Patient Reviews
"I highly recommend Evolve Brain Health if you are considering TMS. My experience was extremely positive. Dr. Knightly is very bright, compassionate and patient. He took time to answer all of my questions without ever making me feel rushed. It’s very easy to schedule appointments and always runs right on time. The treatment is very easy-in and out in less than 15 minutes with no side effects!"
Gerrianne D.
"Dr. Knightly was without a doubt, one of the most professional, knowledgeable and experienced Psychiatrists I have ever seen. Honestly, it was an appointment I would look forward to, rather than just any generic Doctor visit, which we all definitely know is not where we want to be. His follow up and true commitment to his patients is hard to find these days. 5 Stars is not enough. He is better than any rating scale and I know will humbly continue to help as many people as he can."
Michael.
"Dr Knightly is empathetic, professional & informative. He’s walked me through the process & has answered all my questions without hesitation, even the questions I’ve repeatedly asked. During my first session I was overwhelmed with emotion (I’ve tried many things to try to treat my depression) & he validated my experience & made me feel comfortable. I recommend anyone who is interested in TMS to visit his office, you‘re in good hands."
Jade C.
Will My Insurance Cover TMS Therapy?
We can help verify your benefits and provide transparent pricing options so you can plan your treatment confidently.
Featured Resources
Interested in learning about various mental health treatments? Visit our Learning Center for clear, easy-to-understand explanations of procedures, protocols, comparisons, and the conditions they address.
What to Expect In Each Treatment
Beginning therapy can be a daunting experience. By informing you what one might expect from each treatment, we aim to ease this process and minimize the stress around seeking support for your mental health.
Is TMS Therapy Right For Me?
As TMS is a novel approach to mental health treatment, you may not have heard about it. This quiz can help you learn whether you are interested in TMS based on your symptoms, but it is not a comprehensive decision tool.
Our Guide to Help You Choose Your Treatment
Beginning therapy can be difficult enough without being overwhelmed by the variety of treatment options. In this article, we cover the differences between our services to help you decide which treatment you may want to pursue with us.
Book Your Consultation
Take the first step towards better mental health and well-being. Call us at
(203) 504-9758
or complete the form below.
Contact Us
Thank you for contacting us.
We will get back to you as soon as possible.
We will get back to you as soon as possible.
Oops, there was an error sending your message.
Please try again later.
Please try again later.
What Happens In My Consultation?
To create a personalized plan, we assess your medical history, symptoms, and treatment goals.
You'll have an open conversation with your psychiatrist to discuss options and next steps.
A tailored approach is developed based on your unique needs, ensuring the best outcomes for you.
(203) 504-9758
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